One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin.

نویسندگان

  • Cheng Zheng
  • Ai-Xian Zheng
  • Bo Liu
  • Xiao-Long Zhang
  • Yu He
  • Juan Li
  • Huang-Hao Yang
  • Guonan Chen
چکیده

We developed a facile one-step approach to synthesize DNA-templated Ag/Pt bimetallic nanoclusters (DNA-Ag/Pt NCs), which possess highly-efficient peroxidase-like catalytic activity. With this finding, an aptamer based sandwich-type strategy is employed to design a label-free colorimetric aptasensor for the protein detection with high sensitivity and selectivity.

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عنوان ژورنال:
  • Chemical communications

دوره 50 86  شماره 

صفحات  -

تاریخ انتشار 2014